TY  - JOUR 
AU  - Zazo Gómez, Hinojal
AU  - Lagarejos, Eduardo
AU  - Prado-Velasco, Manuel
AU  - Sánchez Herrero, Sergio
AU  - Serna, Jenifer
AU  - Rueda-Ferreiro, Almudena
AU  - Martín Suárez, Ana María
AU  - Calvo Hernández, María Victoria
AU  - Pérez Blanco, Jonás Samuel
AU  - Lanao, José M
PY  - 2022
SN  - 1663-9812
UR  - http://hdl.handle.net/10366/161815
AB  - Each year, infections caused around the 25% of neonatal deaths. Early empirical treatments help to reduce this mortality, although optimized dosing regimens are still lacking. The aims were to develop and validate a gentamicin physiologically-based...
LA  - eng
KW  - PBPK;
KW  - PhysPK software
KW  - TDM
KW  - Dosing evaluation
KW  - Gentamicin
KW  - Neonates
TI  - Physiologically-based pharmacokinetic modelling and dosing evaluation of gentamicin in neonates using PhysPK
DO  - 10.3389/fphar.2022.977372
T2  - Frontiers in pharmacology
VL  - 13
M2  - 977372
ER  -