TY - JOUR AU - Koenis, Duco Steven AU - Beegun, Issa AU - Jouvene, Charlotte Camille AU - Aguirre, Gabriel Amador AU - Souza, Patricia Regina AU - González Núñez, María AU - Ly, Lucy AU - Pistorius, Kimberly AU - Kocher, Hemant M. AU - Ricketts, William AU - Thomas, Gavin AU - Perretti, Mauro AU - Alusi, Ghassan AU - Pfeffer, Paul AU - Dalli, Jesmond PY - 2021 SN - 0009-7330 UR - http://hdl.handle.net/10366/161960 AB - [EN]Rationale: Resolution mechanisms are central in both the maintenance of homeostasis and the return to catabasis following tissue injury and/or infections. Amongst the pro-resolving mediators, the essential fatty acid-derived specialized... LA - eng PB - American Heart Association KW - COVID-19 KW - Leukocytes KW - Lipid mediators KW - Systemic inflammation KW - Monocyte KW - Macrophage KW - Polymorphonuclear neutrophils activation KW - GPCR KW - Omega-3 fatty acids KW - Resolving KW - Phagocytes KW - Inflammation Mediators KW - Humans KW - Cells KW - Neutrophils KW - Leukocytes TI - Disrupted resolution mechanisms favor altered phagocyte responses in COVID-19 DO - 10.1161/CIRCRESAHA.121.319142 T2 - Circulation Research VL - 129 M2 - e54 ER -