TY  - JOUR 
AU  - García Marín, José Juan
AU  - Hernandez, Alicia
AU  - Revuelta, Isabel E.
AU  - Gonzalez-Sanchez, Ester
AU  - González de Buitrago Arriero, José Manuel
AU  - Perez, Maria J.
PY  - 2013
SN  - 0891-5849
UR  - http://hdl.handle.net/10366/162990
AB  - [EN]Acute accumulation of bile acids in hepatocytes may cause cell death. However, during long-term exposure due to prolonged cholestasis, hepatocytes may develop a certain degree of chemoresistance to these compounds. Because mitochondrial adaptation...
LA  - eng
PB  - Elsevier
KW  - Akt
KW  - Apoptosis
KW  - Bcl-2
KW  - Bile Acid
KW  - Cholestasis
KW  - Liver
KW  - Mitochondria
KW  - Retrograde signaling
KW  - Rho cells
KW  - Free radicals
KW  - DNA, Mitochondrial
KW  - Free Radicals
KW  - Apoptosis
KW  - Cholestasis
TI  - Mitochondrial genome depletion in human liver cells abolishes bile acid-induced apoptosis: Role of the Akt/mTOR survival pathway and Bcl-2 family proteins
DO  - 10.1016/J.FREERADBIOMED.2013.04.002
T2  - Free Radical Biology and Medicine
VL  - 61
M2  - 218
ER  -