TY  - JOUR 
AU  - Gutiérrez-Herrero, Sara
AU  - Maia, Vera
AU  - Gutiérrez-Berzal, Javier
AU  - Calzada, Nuria
AU  - Sanz, María
AU  - González-Manchón, Consuelo
AU  - Pericacho, Miguel
AU  - Ortiz-Rivero, Sara
AU  - Arechederra, María
AU  - Porras, Almudena
AU  - Guerrero, Carmen
AU  - González Porras, José Ramón
PY  - 2012
SN  - 0167-4889
UR  - http://hdl.handle.net/10366/163175
AB  - We have generated mouse transgenic lineages for C3G (tgC3G) and C3GΔCat (tgC3GΔCat, C3G mutant lacking the GEF domain), where the transgenes are expressed under the control of the megakaryocyte and platelet specific PF4 (platelet factor 4) gene...
LA  - eng
PB  - Elsevier
KW  - C3G
KW  - Platelet
KW  - Transgenic mice
KW  - Granulocyte
KW  - Neutrophil
KW  - Rap1
KW  - Granulocytes
KW  - rap1 GTP-Binding Proteins
KW  - Rats, Transgenic
KW  - Neutrophils
TI  - C3G transgenic mouse models with specific expression in platelets reveal a new role for C3G in platelet clotting through its GEF activity
DO  - 10.1016/j.bbamcr.2012.05.021
T2  - Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
VL  - 1823
M2  - 1366
ER  -