TY - JOUR AU - Vicente Santiago, María Belén AU - López Abán, Julio AU - Chaccour, Juliane AU - Hernández-Goenaga, Juan AU - Nicolas, Patricia AU - Fernández Soto, Pedro AU - Muro Álvarez, Antonio AU - Chaccour, Carlos PY - 2021 UR - http://hdl.handle.net/10366/163253 AB - Schistosoma mansoni is less susceptible to the antiparasitic drug ivermectin than other helminths. By inhibiting the P-glycoprotein or cytochrome P450 3A in mice host or parasites in a murine model, we aimed at increasing the sensitivity of S. mansoni... LA - eng PB - Nature Publishing Group KW - Ivermectin KW - Cobicistat KW - Elacridar KW - Schistosoma mansoni KW - Ivermectin KW - Schistosoma mansoni KW - Cytochrome P-450 CYP3A KW - Mice TI - The effect of ivermectin alone and in combination with cobicistat or elacridar in experimental Schistosoma mansoni infection in mice. DO - 10.1038/s41598-021-84009-y T2 - Scientific reports VL - 11 M2 - 4476 ER -