TY - JOUR AU - Arévalo-Pérez, Roberto AU - Maderuelo Martín, Cristina AU - Lanao, José M. PY - 2025 UR - http://hdl.handle.net/10366/165054 AB - [EN]Background: Physiologically based biopharmaceutics modeling (PBBM) models can help to predict drug release and in vivo absorption behaviors. Colon drug delivery systems have gained interest over the past few years due to the advantages they... LA - eng PB - Victor Mangas Sanjuán, Inaki F. Troconiz, Maria Garcia-Cremades Mira and Robert D. Arnold KW - SIMCYP KW - Physiologically Based Pharmacokinetic Modeling (PBPK) KW - Physiologically Based Biopharmaceutics Modeling (PBBM) KW - Advanced Dissolution Absorption Model (ADAM) KW - Biopharmaceutical simulations KW - Pharmacokinetics KW - In silico model KW - Drug release KW - Colon Drug Delivery Systems KW - Enteric coating KW - Metronidazole KW - Metronidazole KW - Pharmacokinetics KW - Colon KW - Biopharmaceutics KW - Drug Delivery Systems TI - In Silico Evaluation of the Biopharmaceutical and Pharmacokinetic Behavior of Metronidazole from Coated Colonic Release Matrix Tablets DO - 10.3390/pharmaceutics17050647 T2 - Pharmaceutics VL - 17 M2 - 647 ER -