TY  - JOUR 
AU  - Arévalo-Pérez, Roberto
AU  - Maderuelo, Cristina
AU  - Lanao, José M.
PY  - 2024
SN  - 0928-0987
UR  - http://hdl.handle.net/10366/165075
AB  - [EN] This study aimed to advance the development of intestinal colon-coated sustained-release matrix tablets of metronidazole for diverticulitis treatment, employing the Quality by Design (QbD) methodology. Comprehensive Risk analysis and Risk...
LA  - eng
PB  - Elsevier
KW  - Oral colon delivery
KW  - Metronidazole
KW  - Coated systems
KW  - Diverticulitis disease
KW  - Quality by design (QbD)
KW  - Design space
KW  - Metronidazole
KW  - Colon
KW  - Diverticulitis, Colonic
KW  - Tablets
KW  - Risk Assessment
KW  - Administration, Oral
KW  - Dosage Forms
KW  - Drug Delivery Systems
TI  - Development of intestinal colonic drug delivery systems for diverticular disease: A QbD approach
DO  - 10.1016/j.ejps.2024.106918
T2  - European Journal of Pharmaceutical Sciences
VL  - 203
M2  - 106918
ER  -