TY - JOUR AU - Roberts, Megan N AU - Wallace, Marita A AU - Tomilov, Alexey A AU - Zhou, Zeyu AU - Marcotte, George R AU - Tran, Dianna AU - Perez, Gabriella AU - Gutierrez-Casado, Elena AU - Koike, Shinichiro AU - Knotts, Trina A AU - Imai, Denise M AU - Griffey, Stephen M AU - Kim, Kyoungmi AU - Hagopian, Kevork AU - McMackin, Marissa Z AU - Haj, Fawaz G AU - Baar, Keith AU - Cortopassi, Gino A AU - Ramsey, Jon J AU - López Domínguez, José Alberto PY - 2017 SN - 1932-7420 UR - http://hdl.handle.net/10366/166578 AB - [EN]Calorie restriction, without malnutrition, has been shown to increase lifespan and is associated with a shift away from glycolysis toward beta-oxidation. The objective of this study was to mimic this metabolic shift using low-carbohydrate diets... LA - eng KW - lifespan KW - ketone bodies KW - ketogenic diet KW - memory KW - aging KW - low carbohydrate diet KW - healthspan KW - Diet KW - Longevity TI - A Ketogenic Diet Extends Longevity and Healthspan in Adult Mice. DO - 10.1016/j.cmet.2017.08.005 T2 - Cell metabolism VL - 26 M2 - 539 ER -