TY  - JOUR 
AU  - Chaib, Selim
AU  - López Domínguez, José Alberto
AU  - Lalinde-Gutiérrez, Marta
AU  - Prats, Neus
AU  - Marin, Ines
AU  - Boix, Olga
AU  - García-Garijo, Andrea
AU  - Meyer, Kathleen
AU  - Muñoz, María Isabel
AU  - Aguilera, Mònica
AU  - Mateo, Lidia
AU  - Stephan-Otto Attolini, Camille
AU  - Llanos, Susana
AU  - Pérez-Ramos, Sandra
AU  - Escorihuela, Marta
AU  - Al-Shahrour, Fatima
AU  - Cash, Timothy P
AU  - Tchkonia, Tamara
AU  - Kirkland, James L
AU  - Abad, María
AU  - Gros, Alena
AU  - Arribas, Joaquín
AU  - Serrano, Manuel
AU  - Cash, Timothy P.
AU  - Kirkland, James L.
PY  - 2024
SN  - 2662-1347
UR  - http://hdl.handle.net/10366/166737
AB  - [EN]Chemotherapy often generates intratumoral senescent cancer cells that strongly modify the tumor microenvironment, favoring immunosuppression and tumor growth. We discovered, through an unbiased proteomics screen, that the immune checkpoint...
LA  - eng
KW  - Cellular senescence
KW  - Cancer
KW  - Immunotherapy
KW  - Immune checkpoint ligands
KW  - PD-L2
TI  - The efficacy of chemotherapy is limited by intratumoral senescent cells expressing PD-L2.
DO  - 10.1038/s43018-023-00712-x
T2  - Nature cancer
VL  - 5
M2  - 448
ER  -