TY  - THES 
A3  - García Cenador, María Begoña
A3  - Alcázar Montero, José Antonio
AU  - Boháng, Chen
PY  - 2025
UR  - http://hdl.handle.net/10366/167039
AB  - [ES] La resistencia adquirida a inhibidores de tirosina quinasa (TKIs), como el erlotinib, representa un
desafío clínico importante en el tratamiento del adenocarcinoma pulmonar (LUAD). Este estudio
evalúa el uso de exosomas derivados de células...
AB  - [EN] Lung adenocarcinoma (LUAD) patients frequently develop resistance to tyrosine kinase
inhibitors (TKIs), such as erlotinib, limiting treatment efficacy. In this study, we investigated the
potential of exosomes derived from hBMSCs, loaded with...
LA  - spa
KW  - Tesis y disertaciones académicas
KW  - Universidad de Salamanca (España)
KW  - Academic dissertations
KW  - Adenocarcinoma pulmonar
KW  - Resistencia a erlotinib
KW  - Exosomas
KW  - PTSC3
KW  - Señalización Wnt/ β-catenina
KW  - IncRNA
KW  - Lund adenocarcinoma
KW  - Erlotinib resistance
KW  - Exosomes
KW  - Adenomatosis, Pulmonary
KW  - Exosomes
KW  - Wnt Proteins
KW  - Adenocarcinoma
KW  - beta Catenin
TI  - Exosomes derived from human bone marrow mesenchymal stem cells (hBMSCs)  containing PTCSC3 mitigate erlotinib resistance in lung adenocarcinoma cells through modulation of the Wnt/B-Catenin signaling pathway
M3  - info:eu-repo/semantics/doctoralThesis
DO  - 10.14201/gredos.167039
ER  -