TY - JOUR AU - Blanco Gozalo, Víctor AU - Quirós Luis, Yaremi AU - Vicente Vicente, Rosa Laura AU - Casanova, Alfredo G. AU - Sancho Martínez, Sandra María AU - López Hernández, Francisco José PY - 2024 UR - http://hdl.handle.net/10366/167576 AB - [EN]Nephrotoxicity, including electrolytic disorders and acute kidney injury (AKI), limits the clinical dosage and utility of platinated antineoplastics such as cisplatin. Cisplatin nephrotoxicity embodies a tubulopathy involving the medullary S2 and... LA - eng PB - Elsevier KW - GM2AP KW - acute kidney injury KW - acute tubular injury KW - cisplatin KW - cortical necrosis KW - urinary biomarker KW - Cisplatin KW - Kidney Cortex KW - Gentamicins KW - Severity of Illness Index KW - G(M2) Activator Protein KW - Acute Kidney Injury KW - Rats KW - Animals KW - Antineoplastic Agents TI - Urinary GM2AP coincides with renal cortical damage and grades cisplatin nephrotoxicity severity in rats. DO - 10.1016/j.tox.2024.153919 T2 - Toxicology VL - 508 M2 - 153919 ER -