TY  - JOUR 
AU  - Sotillo, Rocío
AU  - Hernando, Eva
AU  - Díaz Rodríguez, María Elena
AU  - Teruya-Feldstein, Julie
AU  - Cordón-Cardo, Carlos
AU  - Lowe, Scott W
AU  - Benezra, Robert
PY  - 2007
SN  - 1535-6108
UR  - http://hdl.handle.net/10366/167934
AB  - [EN]Mad2 is an essential component of the spindle checkpoint that blocks activation of Separase and dissolution of sister chromatids until microtubule attachment to kinetochores is complete. We show here that overexpression of Mad2 in transgenic mice...
LA  - eng
KW  - DNA
KW  - CELLCYCLE
KW  - HUMDISEASE
KW  - Chromosomal Instability
KW  - Animals
KW  - Humans
KW  - In Situ Hybridization
KW  - Gene Expression
KW  - Mad2 Proteins
KW  - Aneuploidy
KW  - Magnetic Resonance Imaging
KW  - Neoplasms
KW  - Cell Cycle Proteins
KW  - Mice
TI  - Mad2 overexpression promotes aneuploidy and tumorigenesis in mice
DO  - 10.1016/j.ccr.2006.10.019
T2  - Cancer cell
VL  - 11
M2  - 9
ER  -