TY - JOUR AU - Robles Valero, Javier AU - Fernández‐Nevado, Lucía AU - Lorenzo Martín, Luis Francisco AU - Fernández‐Pisonero, Isabel AU - Rodríguez‐Fdez, Sonia AU - Astorga‐Simón, Elsa N PY - 2021 SN - 1460-2075 SN - 0261-4189 UR - http://hdl.handle.net/10366/168546 AB - [EN]Mutations in VAV1, a gene that encodes a multifunctional protein important for lymphocytes, are found at different frequencies in peripheral T-cell lymphoma (PTCL), non-small cell lung cancer, and other tumors. However, their pathobiological... LA - eng PB - Springer Nature Link KW - Angioimmunoblastic T-cell lymphoma KW - Follicular helper T cells KW - Oncogene KW - Peripheral T-cell lymphoma KW - Tumor suppressor KW - GTPases KW - Lymphoma KW - Animals KW - Humans KW - CD4-Positive T-Lymphocytes KW - rac1 GTP-Binding Protein KW - Cell Proliferation KW - COS Cells TI - Cancer-associated mutations in VAV1 trigger variegated signaling outputs and T-cell lymphomagenesis DO - 10.15252/EMBJ.2021108125 T2 - EMBO Journal VL - 40 M2 - 1 ER -