TY - JOUR AU - Linhares, Leonardo Aquino AU - Dos Santos Peixoto, Aline AU - Correia de Sousa, Luanna de Angelis AU - Lucena Laet, João Paulo AU - da Silva Santos, Aline Caroline AU - Alves Pereira, Valeria Rêgo AU - Carneiro Neves, Maria Madileuza AU - Ferreira, Luiz Felipe Gomes Rebello AU - Hernandes, Marcelo Zaldini AU - de la Vega, Jennifer AU - Pereira-Neves, Antônio AU - San Feliciano, Arturo AU - Olmo, Esther Del AU - Schindler, Haiana Charifker AU - Montenegro, Lílian Maria Lapa AU - dos Santos Peixoto, Aline PY - 2023 SN - 0223-5234 UR - http://hdl.handle.net/10366/168756 AB - Tuberculosis remains a major public health problem and one of the top ten causes of death worldwide. The alarming increase in multidrug-resistant and extensively resistant variants (MDR, pre-XDR, and XDR) makes the disease more difficult to treat and... LA - eng KW - Antitubercular drugs Dihydrosphingosine analogues Ethambutol Multidrug resistance KW - Mycobacterium tuberculosis KW - Antitubercular Agents KW - Drug Resistance KW - Ethambutol KW - Microbial Sensitivity Tests KW - Tuberculosis KW - Sphingosine KW - Humans KW - Molecular Docking Simulation TI - In vitro bioevaluation and docking study of dihydrosphingosine and ethambutol analogues against sensitive and multi-drug resistant Mycobacterium tuberculosis. DO - 10.1016/j.ejmech.2023.115579 T2 - European Journal of Medicinal Chemistry VL - 258 M2 - 115579 ER -