TY - JOUR AU - Martínez Buey, Rubén AU - Fernández-Justel, David AU - Jiménez García, Alberto AU - Revuelta Doval, José Luis PY - 2022 SN - 0961-8368 UR - http://hdl.handle.net/10366/168992 AB - [EN]Inosine 5'-monophosphate dehydrogenase (IMPDH) is an evolutionarily conserved enzyme that mediates the first committed step in de novo guanine nucleotide biosynthetic pathway. It is an essential enzyme in purine nucleotide biosynthesis that... LA - eng KW - IMP dehydrogenase KW - Allosteric regulation KW - Nucleotide metabolism KW - Enzyme Inhibitors KW - Guanine Nucleotides KW - Allosteric Regulation KW - Inosine Monophosphate KW - IMP Dehydrogenase TI - The gateway to guanine nucleotides: Allosteric regulation of IMP dehydrogenases. DO - 10.1002/pro.4399 T2 - Protein Science VL - 31 M2 - e4399 ER -