TY  - JOUR 
AU  - Fernández-Justel, David
AU  - Marcos-Alcalde, Íñigo
AU  - Abascal, Federico
AU  - Vidaña, Nerea
AU  - Gómez-Puertas, Paulino
AU  - Jiménez García, Alberto
AU  - Revuelta Doval, José Luis
AU  - Martínez Buey, Rubén
PY  - 2022
SN  - 0961-8368
UR  - http://hdl.handle.net/10366/169002
AB  - [EN]IMP dehydrogenase(IMPDH) is an essential enzyme that catalyzes the rate-limiting step in the guanine nucleotide pathway. In eukaryotic cells, GTP binding to the regulatory domain allosterically controls the activity of IMPDH by a mechanism that is...
LA  - eng
KW  - IMP dehydrogenase
KW  - Bacterial nucleotide metabolism
KW  - Enzyme evolution
KW  - Allosteric regulation
KW  - Bateman domain
KW  - Guanine Nucleotides
KW  - IMP Dehydrogenase
TI  - Diversity of mechanisms to control bacterial GTP homeostasis by the mutually exclusive binding of adenine and guanine nucleotides to IMP dehydrogenase.
DO  - 10.1002/pro.4314
T2  - Protein Science
VL  - 31
M2  - e4314
ER  -