TY - JOUR AU - Estévez-Gallego, Juan AU - Josa-Prado, Fernando AU - Ku, Siou AU - Martínez Buey, Rubén AU - Balaguer, Francisco A AU - Prota, Andrea E AU - Lucena-Agell, Daniel AU - Kamma-Lorger, Christina AU - Yagi, Toshiki AU - Iwamoto, Hiroyuki AU - Duchesne, Laurence AU - Barasoain, Isabel AU - Steinmetz, Michel O AU - Chrétien, Denis AU - Kamimura, Shinji AU - Díaz, J Fernando AU - Oliva, Maria A PY - 2020 UR - http://hdl.handle.net/10366/169007 AB - [EN]Microtubules (MTs) are hollow cylinders made of tubulin, a GTPase responsible for essential functions during cell growth and division, and thus, key target for anti-tumor drugs. In MTs, GTP hydrolysis triggers structural changes in the lattice,... LA - eng KW - Microtubules KW - Tubulin KW - Cryoelectron microscopy KW - X-ray scattering KW - GTP KW - Cryoelectron Microscopy KW - Microtubules KW - Tubulin KW - Guanosine Triphosphate TI - Structural model for differential cap maturation at growing microtubule ends DO - 10.7554/eLife.50155 T2 - eLife VL - 9 M2 - e50155 ER -