TY - JOUR AU - Calvo Baltanás, Fernando AU - Pérez Andrés, Martín AU - Ginel Picardo, Alicia AU - Díaz López, David AU - Jimeno, David AU - Liceras Boillos, Pilar AU - Kortum, Robert AU - Samelson, Lawrence E. AU - Orfao de Matos Correia e Vale, José Alberto AU - Santos de Dios, Eugenio Miguel PY - 2013 UR - http://hdl.handle.net/10366/169118 AB - [EN] Sos1 and Sos2 are ubiquitously expressed, universal Ras guanine nucleotide exchange factors (Ras-GEFs) acting in multiple signal transduction pathways activated by upstream cellular kinases. The embryonic lethality of Sos1 null mutants has... LA - eng PB - Taylor & Francis KW - SOS1 Protein KW - Bone marrow transplant KW - B-Lymphocytes KW - T-Lymphocytes KW - B-Lymphocytes KW - T-Lymphocytes KW - Lymphopoiesis KW - Homeostasis KW - SOS1 Protein KW - Animals KW - Son of Sevenless Proteins KW - Lymphoid Progenitor Cells KW - Cell Count KW - Mice TI - Functional redundancy of Sos1 and Sos2 for lymphopoiesis and organismal homeostasis and survival. DO - 10.1128/MCB.01026-13 T2 - Molecular and cellular biology VL - 33 M2 - 4562 ER -