TY - JOUR AU - Asensio Martín, Maitane AU - Briz Sánchez, Oscar AU - Herráez Aguilar, Elisa AU - Perez Silva, Laura AU - Espinosa Escudero, Ricardo Antonio AU - Bueno-Sacristan, Diego AU - Peleteiro Vigil, Ana AU - Hammer, Helen AU - Pötz, Oliver AU - Kadioglu, Onat AU - Banales, Jesus M AU - Martinez-Chantar, Maria L AU - Avila, Matias A AU - Rodríguez Macías, Rocío Isabel AU - Efferth, Thomas AU - García Marín, José Juan AU - Lozano, Elisa PY - 2024 SN - 1950-6007 | 0753-3322 UR - http://hdl.handle.net/10366/169140 AB - [EN]Drug export through ABC proteins hinders cancer response to chemotherapy. Here, we have evaluated the relevance of MRP3 (ABCC3) in cholangiocarcinoma (CCA) as a potential target to overcome drug resistance. Gene expression was analyzed in silico... LA - eng PB - ELSEVIER KW - ABC transporters KW - Biliary tract cancer KW - Chemosensitization KW - Tyrosine kinase inhibitors KW - Natural products KW - Cisplatin KW - Cholangiocarcinoma KW - HEK293 Cells KW - Xenograft Model Antitumor Assays KW - Humans KW - Multidrug Resistance-Associated Proteins KW - Cell Line KW - Antineoplastic Agents KW - Molecular Docking Simulation KW - Bile Duct Neoplasms KW - Drug Resistance KW - Animals KW - Mice TI - Sensitizing cholangiocarcinoma to chemotherapy by inhibition of the drug-export pump MRP3. DO - 10.1016/j.biopha.2024.117533 T2 - Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie VL - 180 M2 - 117533 ER -