TY - JOUR AU - Llano Cuadra, María Elena AU - Todeschini, Anne Laure AU - Felipe-Medina, Natalia AU - Corte-Torres, María D AU - Condezo, Yazmine B AU - Sánchez Martín, Manuel Adolfo AU - López-Tamargo, Sara AU - Astudillo, Aurora AU - Puente, Xose S AU - Pendás, Alberto M. AU - Veitia, Reiner A PY - 2023 UR - http://hdl.handle.net/10366/169199 AB - [EN]Adult-type granulosa cell tumors (AGCT) are the most common type of malignant ovarian sex cord-stromal tumors. Most AGCTs carry the somatic variant c.402C>G (p.C134W) affecting the transcription factor FOXL2. Germline dominant variants in FOXL2... LA - eng KW - Granuloda cell tumors KW - FOXL2 KW - mouse model KW - Forkhead Transcription Factors KW - Mutation KW - Adult KW - Skin Abnormalities KW - Ovarian Neoplasms KW - Animals KW - Humans KW - Granulosa Cell Tumor KW - Blepharophimosis KW - Urogenital Abnormalities KW - Mice TI - The Oncogenic FOXL2 C134W Mutation Is a Key Driver of Granulosa Cell Tumors. DO - 10.1158/0008-5472.CAN-22-1880 T2 - Cancer Research VL - 83 M2 - 239 ER -