TY  - JOUR 
AU  - Quirós Luis, Yaremi
AU  - Vicente Vicente, Rosa Laura
AU  - Morales Martín, Ana Isabel
AU  - López-Novoa, José M.
AU  - López Hernández, Francisco José
PY  - 2011
SN  - 1096-6080
UR  - http://hdl.handle.net/10366/169383
AB  - [EN]Gentamicin is an aminoglycoside antibiotic widely used against infections by Gram-negative microorganisms. Nephrotoxicity is the main limitation to its therapeutic efficacy. Gentamicin nephrotoxicity occurs in 10-20% of therapeutic regimes. A...
LA  - eng
PB  - Oxford University Press
KW  - Gentamicin
KW  - Aminoglycoside antibiotics
KW  - Cytotoxicity
KW  - Apoptosis
KW  - Necrosis
KW  - Nephrotoxicity
KW  - Kidney
KW  - Gentamicins
KW  - Protein Denaturation
KW  - Kidney Tubules
KW  - Phospholipids
KW  - Subcellular Fractions
KW  - Apoptosis
KW  - Anti-Bacterial Agents
KW  - Animals
KW  - Humans
TI  - An integrative overview on the mechanisms underlying the renal tubular cytotoxicity of gentamicin
DO  - 10.1093/toxsci/kfq267
VL  - 119
M2  - 245
ER  -