TY - JOUR AU - Liceras Boillos, Pilar AU - Jimeno García, David AU - García Navas, Rósula Mercedes AU - Lorenzo Martín, Luis Francisco AU - Menacho Márquez, Mauricio Ariel AU - Segrelles, Carmen AU - Gómez Rodríguez, Carmela AU - Calzada, Nuria AU - Fuentes Mateos, Rocío AU - Paramio, Jesús M AU - Bustelo, Xosé R. AU - Baltanás, Fernando C. AU - Santos de Dios, Eugenio Miguel PY - 2018 UR - http://hdl.handle.net/10366/169724 AB - [EN]ABSTRACT Using Sos1 knockout (Sos1-KO), Sos2-KO, and Sos1/2 double-knockout (Sos1/2-DKO) mice, we assessed the functional role of Sos1 and Sos2 in skin homeostasis under physiological and/or pathological conditions. Sos1 depletion resulted... LA - eng PB - Taylor and Francis Group KW - RasGEFs KW - Sos1 KW - Sos2 KW - Skin tumors KW - ras Proteins KW - Carcinogenesis TI - Differential role of the RasGEFs Sos1 and Sos2 in mouse skin homeostasis and carcinogenesis DO - 10.1128/MCB.00049-18 T2 - Molecular and Cellular Biology VL - 38 ER -