TY - JOUR AU - Zapata-Pavas, L Estefanía AU - Serrano-Macia, Marina AU - Merlos Rodrigo, Miguel Ángel AU - Barrenechea-Barrenechea, Jon Ander AU - Peña-SanFelix, Patricia AU - Del Río-Álvarez, Álvaro AU - Gil-Pitarch, Clàudia AU - Rejano-Gordillo, Claudia M AU - Goikoetxea-Usandizaga, Naroa AU - González-Recio, Irene AU - Michalkova, Hana AU - Mercado-Gómez, Maria AU - Lachiondo-Ortega, Sofia AU - Castañeda, Andrea AU - Asensio Martín, Maitane AU - Murti, Abhishek AU - Lelou, Elise AU - Nogueiras, Rubén AU - Mayor, Ugo AU - Heger, Zbynek AU - Sancho-Bru, Pau AU - Delgado, Teresa C AU - Calvisi, Diego F AU - Xirodimas, Dimitris P AU - Wang, Bruce AU - Marin, Jose J G AU - Fernandez-Barrena, Maite G AU - Armengol, Carolina AU - Ávila, Matías AU - Martínez-Chantar, María Luz PY - 2025 SN - 0270-9139 UR - http://hdl.handle.net/10366/170066 AB - [EN]Hepatoblastoma (HB) is the most common malignant liver tumor in children. Despite advances in multimodal treatment, chemoresistance and relapses remain major clinical challenges. NEDDylation, a post-translational modification involving the... LA - eng PB - Lippincott Williams and Wilkins KW - molecular oncology KW - Pediatric liver cancer KW - Posttranslational regulation KW - Therapeutic target KW - Ubiquitin-like modification TI - NEDD8-specific protease 1 deficiency as a novel driver of hepatoblastoma development through dysregulation of the CAND1-NEDD8 pathway DO - 10.1097/HEP.0000000000001614 T2 - Hepatology ER -