TY  - JOUR 
AU  - Hurtado-Navarro, Laura
AU  - Cuenca-Zamora, Ernesto José
AU  - Zamora, Lurdes
AU  - Bellosillo, Beatriz
AU  - Such, Esperanza
AU  - Soler-Espejo, Eva
AU  - Martínez-Banaclocha, Helios
AU  - Hernández Rivas, Jesús María
AU  - Marco-Ayala, Javier
AU  - Martínez-Alarcón, Laura
AU  - Linares-Latorre, Lola
AU  - García-Ávila, Sara
AU  - Amat-Martínez, Paula
AU  - González, Teresa
AU  - Arnan, Montserrat
AU  - Pomares-Marín, Helena
AU  - Carreño-Tarragona, Gonzalo
AU  - Chen-Liang, Tzu Hua
AU  - Herranz, María T
AU  - García-Palenciano, Carlos
AU  - Morales, María Luz
AU  - Jerez, Andrés
AU  - Lozano, María L
AU  - Teruel-Montoya, Raúl
AU  - Pelegrín, Pablo
AU  - Ferrer-Marín, Francisca
PY  - 2023
UR  - http://hdl.handle.net/10366/172040
AB  - [EN]Chronic myelomonocytic leukemia (CMML) is frequently associated with mutations in the rat sarcoma gene (RAS), leading to worse prognosis. RAS mutations result in active RAS-GTP proteins, favoring myeloid cell proliferation and survival and...
LA  - eng
KW  - Inflammasomes
KW  - Leukemia, Myelomonocytic, Chronic
KW  - Humans
KW  - NLR Family, Pyrin Domain-Containing 3 Protein
KW  - Proto-Oncogene Proteins p21(ras)
KW  - Symptom Burden
KW  - Interleukin-1
KW  - Proto-Oncogene Proteins p21(ras)
KW  - Interleukin-1
KW  - Leukemia
KW  - Inflammasomes
KW  - Humans
TI  - NLRP3 inflammasome activation and symptom burden in KRAS-mutated CMML patients is reverted by IL-1 blocking therapy
DO  - 10.1016/j.xcrm.2023.101329
T2  - Cell reports. Medicine
VL  - 4
M2  - 101329
ER  -