Título
Effect of the structure and concentration of cyclodextrins in the quenching process of naproxen
Autor(es)
Palabras clave
Quenching
Naproxen
Hydroxypropyl
alpha-Cyclodextrins
beta-Cyclodextrins
Fecha de publicación
2006-11-15
Editor
Elsevier
Citación
Valero, López-Cornejo, & Costa. (2007). Effect of the structure and concentration of cyclodextrins in the quenching process of naproxen. Journal of Photochemistry and Photobiology A: Chemistry, 188(1), 5-11. https://doi.org/10.1016/J.JPHOTOCHEM.2006.11.011
Resumen
[EN]The effect of the formation of the naproxen:cyclodextrin inclusion complex on the quenching of the drug by iodide has been studied. The results
show that -cyclodextrin ( -CD), -cyclodextrin ( -CD), and hydroxypropyl- -cyclodextrin (HP- -CD) provide good protection for the drug
against iodide quenching. The trend of protection is -CD > HP- -CD≈ -CD>H2O, in contrast to the binding constant values and the structure
of these complexes. The effect of these cyclodextrins on the quenching process is discussed on the basis of the parameters obtained by fitting the
experimental data to the modified Stern–Volmer, and finite-sink approximation models.
URI
ISSN
1010-6030
DOI
10.1016/J.JPHOTOCHEM.2006.11.011
Versión del editor
Aparece en las colecciones
