TY - JOUR AU - Hijazi Vega, Maruan AU - Fillat, Cristina AU - Medina Jiménez, José María AU - Velasco Criado, Ana Purificación PY - 2013 SN - 0014-4886 UR - http://hdl.handle.net/10366/155088 AB - [EN]Histological brain studies of individuals with DS have revealed an aberrant formation of the cerebral cortex. Previous work from our laboratory has shown that oleic acid acts as a neurotrophic factor and induces neuronal differentiation. In order... LA - eng PB - Elsevier KW - Down syndrome KW - Genotype KW - Transfection KW - Cell Differentiation KW - Choline O-Acetyltransferase KW - Humans KW - Down Syndrome KW - Cell Line KW - Nerve Growth Factors KW - RNA KW - Enzyme Induction KW - Immunohistochemistry KW - Protein-Tyrosine Kinases KW - Animals KW - Polymerase Chain Reaction KW - Trisomy KW - Oleic Acid KW - Mice TI - Overexpression of DYRK1A inhibits choline acetyltransferase induction by oleic acid in cellular models of Down syndrome DO - 10.1016/j.expneurol.2012.10.016 T2 - Experimental neurology VL - 239 M2 - 229 ER -