TY  - JOUR 
AU  - Quijada Álamo, Miguel
AU  - Hernández Sánchez, María
AU  - Rodríguez Vicente, Ana E.
AU  - Pérez Carretero, Claudia
AU  - Rodríguez-Sánchez, Alberto
AU  - Martín Izquierdo, Marta
AU  - Alonso-Pérez, Verónica
AU  - García-Tuñón, Ignacio
AU  - Bastida Bermejo, José María
AU  - Vidal-Manceñido, María Jesús
AU  - Galende, Josefina
AU  - Aguilar, Carlos
AU  - Queizán, José Antonio
AU  - González-Gascón y Marín, Isabel
AU  - Hernández Rivas, José Ángel
AU  - Benito Sánchez, Rocío
AU  - Ordóñez García, José Luis
AU  - Hernández Rivas, Jesús María
PY  - 2021
UR  - http://hdl.handle.net/10366/158982
AB  - [EN]BIRC3 is monoallelically deleted in up to 80% of chronic lymphocytic leukemia (CLL) cases harboring del(11q). In addition, truncating mutations in the remaining allele of this gene can lead to BIRC3 biallelic inactivation, which has been shown to...
LA  - eng
PB  - SPRINGER NATURE
KW  - Chronic lymphocytic leukemia
KW  - CLL
KW  - CRISPR
KW  - BIRC3
KW  - Farmacología
KW  - 11q deletion
KW  - Pharmacology
KW  - Leukemia
KW  - CRISPR-Cas Systems
TI  - Biological significance of monoallelic and biallelic BIRC3 loss in del(11q) chronic lymphocytic leukemia progression
DO  - 10.1038/S41408-021-00520-5
T2  - Blood Cancer Journal
VL  - 11
ER  -