TY  - JOUR 
AU  - Marques, Raquel M
AU  - González Núñez, María
AU  - Walker, Mary E
AU  - Gomez, Esteban A
AU  - Colas, Romain A
AU  - Montero-Melendez, Trinidad
AU  - Perretti, Mauro
AU  - Dalli, Jesmond
PY  - 2021
SN  - 1350-9047
UR  - http://hdl.handle.net/10366/161762
AB  - [EN]Regulatory T-cells (Tregs) are central in the maintenance of homeostasis and resolution of inflammation. However, the mechanisms that govern their differentiation and function are not completely understood. Herein, we demonstrate a central role...
LA  - eng
KW  - Animals
KW  - Arachidonate 15-Lipoxygenase
KW  - Cell Differentiation
KW  - Healthy Volunteers
KW  - Humans
KW  - Male
KW  - T-Lymphocytes, Regulatory
KW  - Up-Regulation
KW  - T-Lymphocytes
KW  - Arachidonate 15-Lipoxygenase
KW  - Animals
KW  - Cell Differentiation
KW  - Humans
KW  - Healthy Volunteers
KW  - Up-Regulation
KW  - Mice
TI  - Loss of 15-lipoxygenase disrupts Treg differentiation altering their pro-resolving functions.
DO  - 10.1038/s41418-021-00807-x
T2  - Cell death and differentiation
VL  - 28
M2  - 3140
ER  -