TY  - JOUR 
AU  - Abdelfatah, Sara
AU  - Böckers, Madeleine
AU  - Asensio Martín, Maitane
AU  - Kadioglu, Onat
AU  - Klinger, Anette
AU  - Fleischer, Edmond
AU  - Efferth, Thomas
PY  - 2021
SN  - 0944-7113
UR  - http://hdl.handle.net/10366/170057
AB  - [EN]A major problem of cancer treatment is the development of multidrug resistance (MDR) to chemotherapy. MDR is caused by different mechanisms such as the expression of the ABC-transporters P-glycoprotein (P-gp, MDR1, ABCB1) and breast cancer...
LA  - eng
PB  - Elsevier GmbH
KW  - ABC-transporter
KW  - Multidrug-resistance
KW  - Natural products
KW  - P-glycoprotein
KW  - Petasites formosanus
KW  - Drug Resistance
KW  - Neoplasm Proteins
KW  - Humans
KW  - Sesquiterpenes
KW  - Cell Line
KW  - Molecular Docking Simulation
TI  - Isopetasin and S-isopetasin as novel P-glycoprotein inhibitors against multidrug-resistant cancer cells
DO  - 10.1016/J.PHYMED.2020.153196
T2  - Phytomedicine
VL  - 86
M2  - 153196
ER  -