TY - JOUR AU - Emlet, David R. AU - Gupta, Puja AU - Holgado Madruga, Marina AU - Del Vecchio, Catherine A. AU - Mitra, Siddhartha S. AU - Han, Shuang-Yin AU - Li, Gordon AU - Jensen, Kristin C. AU - Vogel, Hannes AU - Xu, Linda Wei AU - Skirboll, Stephen S. AU - Wong, Albert J. PY - 2014 SN - 0008-5472 UR - http://hdl.handle.net/10366/171010 AB - [EN]The relationship between mutated proteins and the cancer stem-cell population is unclear. Glioblastoma tumors frequently express EGFRvIII, an EGF receptor (EGFR) variant that arises via gene rearrangement and amplification. However, expression of... LA - eng PB - AACR KW - Glioblastoma KW - EGFRvIII KW - Cancer Stem Cells KW - CD133 (Prominin-1) KW - Tumor-Initiating Cells KW - Self-Renewal KW - Bispecific Antibodies KW - Targeted Therapy KW - Antibodies, Bispecific KW - Molecular Targeted Therapy KW - Neoplastic Stem Cells TI - Targeting a Glioblastoma Cancer Stem-Cell Population Defined by EGF Receptor Variant III DO - 10.1158/0008-5472.CAN-13-1407 T2 - Cancer Research VL - 74 M2 - 1238 ER -