TY  - JOUR 
AU  - García Domingo, Mónica
AU  - Dogusan, Zeynep
AU  - Moore, Fabrice
AU  - Sato, Shintaro
AU  - Hartmann, Gunther
AU  - Eizirik, Decio L
AU  - Rasschaert, Joanne
AU  - Eizirik, Decio L.
PY  - 2009
SN  - 0006-3002
SN  - 0167-4889
UR  - http://hdl.handle.net/10366/171495
AB  - [EN]Enteroviral infections are associated with type I diabetes. The mechanisms by which viruses or viral products such as double-stranded RNA (dsRNA) affect pancreatic beta cell function and survival remain unclear. We have shown that extracellular...
LA  - eng
KW  - Diabetes
KW  - RNA helicases
KW  - Toll-like receptor 3
KW  - Apoptosis
KW  - Insulin-Secreting Cells
KW  - Gene Deletion
KW  - Poly I-C
KW  - Enterovirus Infections
KW  - Nerve Tissue Proteins
KW  - Gene Expression Regulation
KW  - Cytosol
KW  - Enterovirus
KW  - Membrane Proteins
KW  - RNA
KW  - NF-kappa B
KW  - Toll-Like Receptor 3
KW  - Apoptosis
KW  - Rats
KW  - Animals
KW  - DEAD-box RNA Helicases
KW  - Interferon-beta
KW  - Up-Regulation
KW  - Mice
TI  - Regulation and function of the cytosolic viral RNA sensor RIG-I in pancreatic beta cells
DO  - 10.1016/j.bbamcr.2009.09.005
T2  - Biochimica et Biophysica Acta - Molecular Cell Research
VL  - 1793
M2  - 1768
ER  -