TY - JOUR AU - Mecklenbrauck, Rabea AU - Villaverde Ramiro, Ángela AU - Sträng, Eric AU - Gabdoulline, Razif AU - Martínez Elicegui, Javier AU - Sobas, Marta AU - Pleyer, Lisa AU - Turki, Amin T. AU - Voso, Maria Teresa AU - Benner, Axel AU - Hernández Sánchez, Alberto AU - Tettero, Jesse M. AU - Tur Gimenez, Laura AU - Metzeler, Klaus H. AU - Oñate, Guadalupe AU - Lehmann, Sören AU - Huntly, Brian JP AU - Thomas, Ian AU - Thol, Felicitas R. AU - Heidel, Florian H. AU - Valk, Peter JM AU - Döhner, Konstanze AU - Haferlach, Torsten AU - Mills, Kenneth I. AU - Döhner, Hartmut AU - Castellani, Gastone AU - Ossenkoppele, Gert J. AU - Hernández Rivas, Jesús María AU - Bullinger, Lars AU - Heuser, Michael PY - 2026 UR - http://hdl.handle.net/10366/172022 AB - [EN]The inclusion of nine myelodysplasia-related gene (MRG) mutations (ASXL1, BCOR, EZH2, RUNX1, SF3B1, SRSF2, STAG2, U2AF1, ZRSR2) as adverse risk factors in the ELN risk classification has reshaped classification in acute myeloid leukemia (AML). AML... LA - eng PB - Springer Nature [academic journals on nature.com] KW - fms-Like Tyrosine Kinase 3 KW - Leukemia, Myeloid, Acute KW - Mutation KW - Myelodysplastic Syndromes KW - Humans KW - Nucleophosmin KW - Prognosis KW - Nuclear Proteins KW - Female KW - Prognosis KW - Mutation KW - Leukemia, Myeloid, Acute KW - Humans KW - fms-Like Tyrosine Kinase 3 KW - Myelodysplastic Syndromes KW - Nuclear Proteins TI - Prognostic impact of myelodysplasia-related gene mutations in FLT3-ITD-mutated acute myeloid leukemia DO - 10.1038/s41375-026-02874-w T2 - Leukemia VL - 40 M2 - 622 ER -