TY  - JOUR 
AU  - Carmen Martínez, Sofía del
AU  - Sayagués Manzano, José María
AU  - Bengoechea Miranda, Oscar
AU  - Anduaga, María Fernanda
AU  - Alcázar Montero, José Antonio
AU  - Gervas Ruth
AU  - Herráez García, Jacinto Faustino
AU  - Orfao de Matos Correia e Vale, José Alberto
AU  - Muñoz Bellvís, Luis
AU  - Sarasquete, M. Eugenia
AU  - Abad Hernández, María Mar
PY  - 2018
UR  - http://hdl.handle.net/10366/146620
AB  - [EN] It is well known that activating mutations in the KRAS and NRAS genes are associated with poor response to anti-EGFR therapies in patients with metastatic colorectal cancer (mCRC). Approximately half of the patients with wild-type (WT) KRAS...
LA  - eng
PB  - Impact Journals LLC
KW  - Anti-EGFR
KW  - Clonal evolution
KW  - Colorectal cancer
KW  - Mutational profile
KW  - Tumor heterogeneity
KW  - Colorectal Surgery
KW  - Clonal Evolution
TI  - Spatio-temporal tumor heterogeneity in metastatic CRC tumors: a mutational-based approach
DO  - 10.18632/oncotarget.26081
T2  - Oncotarget
VL  - 9
M2  - 34279
ER  -