TY  - JOUR 
AU  - Hernández Sánchez, Alberto
AU  - Villaverde Ramiro, Ángela
AU  - Sträng, Eric
AU  - Turki, Amin T.
AU  - Abáigar, María
AU  - Versluis, Jurjen
AU  - Thomas, Ian
AU  - Sobas, Marta
AU  - Martínez Elicegui, Javier
AU  - Castellani, Gastone
AU  - Benner, Axel
AU  - Azibeiro, Raúl
AU  - Tettero, Jesse M.
AU  - Mecklenbrauck, Rabea
AU  - Martínez López, Joaquín
AU  - Pratcorona, Marta
AU  - Mills, Ken I
AU  - Sanz, Guillermo
AU  - Voso, María Teresa
AU  - Sören, Lehmann
AU  - Röllig, Christoph
AU  - Thiede, Christian
AU  - Metzeler, Klaus H.
AU  - Döhner, Konstanze
AU  - Heuser, Michael
AU  - Haferlach, Torsten
AU  - Valk, Peter J. M.
AU  - Rusell, Nigel
AU  - Hernández Rivas, Jesús María
AU  - Huntly, Brian
AU  - Ossenkoppele, Gert
AU  - Döhner, Hartmut
AU  - Bullinger, Lars
PY  - 2026
UR  - http://hdl.handle.net/10366/172020
AB  - [EN]NPM1-mutated (NPM1-mut) acute myeloid leukemia (AML) is generally associated with a more favorable outcome, although the presence of additional gene mutations can influence patient prognosis. We analyzed intensively-treated adult NPM1-mut AML...
LA  - eng
PB  - Springer Nature [academic journals on nature.com]
KW  - Leukemia, Myeloid, Acute
KW  - Mutation
KW  - Nuclear Proteins
KW  - Biomarkers, Tumor
KW  - Humans
KW  - Nucleophosmin
KW  - Prognosis
KW  - Adult
KW  - Female
KW  - Middle Aged
KW  - Male
KW  - Aged
KW  - DNA Methyltransferase 3A
KW  - Dioxygenases
KW  - fms-Like Tyrosine Kinase 3
KW  - DNA-Binding Proteins
KW  - Isocitrate Dehydrogenase
KW  - Young Adult
KW  - DNA (Cytosine-5-)-Methyltransferases
KW  - Proto-Oncogene Proteins
KW  - Aged
KW  - Young Adult
KW  - Leukemia
KW  - Adult
KW  - Humans
KW  - DNA-Binding Proteins
KW  - Proto-Oncogene Proteins
KW  - Middle Aged
KW  - Dioxygenases
KW  - Nuclear Proteins
KW  - Isocitrate Dehydrogenase
KW  - Prognosis
KW  - Mutation
KW  - fms-Like Tyrosine Kinase 3
TI  - Unravelling co-mutational patterns with prognostic implications in NPM1 mutated adult acute myeloid leukemia - a HARMONY study
DO  - 10.1038/s41375-025-02851-9
T2  - Leukemia
VL  - 40
M2  - 418
ER  -