TY - THES A3 - Gómez Nieto, Ricardo José A3 - López García, María Dolores AU - López Pérez, Luis PY - 2026 UR - http://hdl.handle.net/10366/172738 AB - [ES]Introducción: La amiloidosis por transtiretina (ATTR) es una enfermedad sistémica progresiva causada por el depósito extracelular de fibrillas derivadas de transtiretina (TTR) mal plegada. La desestabilización del tetrámero de TTR (por mutaciones... AB - [ENIntroduction: Transthyretin amyloidosis (ATTR) is a progressive systemic disease caused by the extracellular deposition of fibrils derived from misfolded transthyretin (TTR). The destabilization of the TTR tetramer (due to autosomal dominant... AB - [ENIntroduction: Transthyretin amyloidosis (ATTR) is a progressive systemic disease caused by the extracellular deposition of fibrils derived from misfolded transthyretin (TTR). The destabilization of the TTR tetramer (due to autosomal dominant... LA - spa KW - Transtiretina KW - ATTR KW - Amiloidosis KW - GASH/Sal KW - Mesocricetus auratus KW - Bioinformática estructural KW - Rojo Congo KW - Modelo animal KW - Amiloidogénesis KW - Epilepsia audiogénica KW - Transthyretin KW - Amyloidosis KW - Mesocricetus auratus KW - Structural bioinformatics KW - Congo red KW - Animal model KW - Amyloidosis KW - Audiogenic epilepsy KW - Epilepsy KW - Amyloidosis KW - Mesocricetus TI - Evaluación del potencial del hámster GASH/Sal como modelo traslacional de amiloidosis por transtiretina mediante análisis in silico e histológico T2 - Evaluation of the GASH/Sal hamster as a potential translational model for transthyretin amyloidosis through in silico and histological analysis M3 - info:eu-repo/semantics/bachelorThesis ER -