TY  - JOUR 
AU  - Martín Marcos, Pilar
AU  - Zhou, Fujun
AU  - Karunasiri, Charm
AU  - Zhang, Fan
AU  - Dong, Jinsheng
AU  - Nanda, Jagpreet
AU  - Kulkarni, Shardul D
AU  - Sen, Neelam Dabas
AU  - Tamame González, Mercedes
AU  - Zeschnigk, Michael
AU  - Lorsch, Jon R
AU  - Hinnebusch, Alan G
PY  - 2017
UR  - http://hdl.handle.net/10366/140726
AB  - [EN] The translation pre-initiation complex (PIC) scans the mRNA for an AUG codon in
favorable context, and AUG recognition stabilizes a closed PIC conformation. The unstructured
N-terminal tail (NTT) of yeast eIF1A deploys five basic residues to...
LA  - eng
PB  - Nahum Sonenberg, McGill University, Canada
KW  - Instituto de Biología Funcional y Genómica
KW  - Biochemistry
KW  - Chemical biology
KW  - eIF1A residues
KW  - Pre-initiation complex
KW  - Uveal melanoma
KW  - Yeast
KW  - Yeasts
TI  - eIF1A residues implicated in cancer stabilize translation preinitiation complexes and favor suboptimal initiation sites in yeast
DO  - 10.7554/eLife.31250
T2  - eLife
VL  - 6
M2  - 1
ER  -