TY  - JOUR 
AU  - Darrière, Tommy
AU  - Pilsl, Michael
AU  - Sarthou, Marie-Kerguelen
AU  - Chauvier, Adrien
AU  - Genty, Titouan
AU  - Audibert, Sylvain
AU  - Dez, Christophe
AU  - Léger-Silvestre, Isabelle
AU  - Normand, Christophe
AU  - Henras, Anthony K.
AU  - Kwapisz, Marta
AU  - Calvo García, Olga María
AU  - Fernández-Tornero, Carlos
AU  - Tschochner, Herbert
AU  - Gadal, Olivier
PY  - 2019
UR  - http://hdl.handle.net/10366/146280
AB  - [EN]Most transcriptional activity of exponentially growing cells is carried out by the RNA Polymerase I (Pol I), which produces a ribosomal RNA (rRNA) precursor. In budding yeast, Pol I is a multimeric enzyme with 14 subunits. Among them, Rpa49 forms...
LA  - eng
PB  - PloS Genetics
KW  - Genetic
KW  - RNA Polymerase
KW  - Rpa49
KW  - Super-active mutant
KW  - Biochemical analysis
KW  - Enzyme
KW  - RNA Polymerase I
TI  - Genetic analyses led to the discovery of a super-active mutant of the RNA polymerase I
DO  - 10.1371/journal.pgen.1008157
T2  - PLOS Genetics
VL  - 15
M2  - e1008157
ER  -