TY  - JOUR 
AU  - Naia, Luana
AU  - Carmo, Catarina
AU  - Campesan, Susanna
AU  - Fão, Lígia
AU  - Cotton, Victoria E.
AU  - Valero , Jorge
AU  - Lopes, Carla
AU  - Rosenstock, Tatiana R.
AU  - Giorgini, Flaviano
AU  - Rego, Ana Cristina
PY  - 2021
SN  - 0891-5849
UR  - http://hdl.handle.net/10366/154467
AB  - SIRT3 is a major regulator of mitochondrial acetylome. Here we show that SIRT3 is neuroprotective in Huntington's disease (HD), a motor neurodegenerative disorder caused by an abnormal expansion of polyglutamines in the huntingtin protein (HTT)....
LA  - spa
KW  - Huntington disease
KW  - Mitochondrial dynamics
KW  - Mitochondrial function
KW  - Oxidative stress
KW  - SIRT3
TI  - Mitochondrial SIRT3 confers neuroprotection in Huntington's disease by regulation of oxidative challenges and mitochondrial dynamics
DO  - 10.1016/j.freeradbiomed.2020.11.031
T2  - Free Radical Biology and Medicine
VL  - 163
M2  - 163
ER  -