TY  - JOUR 
AU  - Lechertier, Tanguy
AU  - Reynolds, Louise E.
AU  - Kim, Hyojin
AU  - Pedrosa, Ana Rita
AU  - Gómez Escudero, Jesús
AU  - Muñoz Félix, José Manuel
AU  - Batista, Silvia
AU  - Dukinfield, Matthew
AU  - Demircioglu, Fevzi
AU  - Wong, Ping Pui
AU  - Matchett, Kylie P.
AU  - Henderson, Neil C.
AU  - D'Amico, Gabriela
AU  - Parsons, Maddy
AU  - Harwood, Catherine
AU  - Meier, Pascal
AU  - Hodivala-Dilke, Kairbaan M.
PY  - 2020
UR  - http://hdl.handle.net/10366/154586
AB  - [EN]The overexpression of the protein tyrosine kinase, Focal adhesion kinase (FAK), in endothelial cells has implicated its requirement in angiogenesis and tumour growth, but how pericyte FAK regulates tumour angiogenesis is unknown. We show that...
LA  - eng
PB  - Nature Research
KW  - Melanoma
KW  - Tumoral
KW  - Focal Adhesion Kinase 1
KW  - Pericytes
KW  - Vascular Endothelial Growth Factor A
KW  - Cell Adhesion
KW  - Aorta
KW  - Carcinoma
KW  - Gene Expression Regulation
KW  - Humans
KW  - Proto-Oncogene Proteins
KW  - Melanoma
KW  - Cell Proliferation
KW  - Neoplasms
KW  - Proto-Oncogene Proteins c-sis
KW  - Receptor Protein-Tyrosine Kinases
KW  - Lymphokines
KW  - Tumor Microenvironment
KW  - Platelet-Derived Growth Factor
KW  - Animals
KW  - Cysteine-Rich Protein 61
KW  - Intercellular Signaling Peptides and Proteins
KW  - Signal Transduction
KW  - Mice
TI  - Pericyte FAK negatively regulates Gas6/Axl signalling to suppress tumour angiogenesis and tumour growth
DO  - 10.1038/s41467-020-16618-6
T2  - Nature Communications
VL  - 11
ER  -