TY - JOUR AU - Mattingly, Mark AU - Seidel, Chris AU - Muñoz Félix, Sofía AU - Hao, Yan AU - Zhang, Ying AU - Wen, Zhihui AU - Florens, Laurence AU - Uhlmann, Frank AU - Gerton, Jennifer L PY - 2022 UR - http://hdl.handle.net/10366/154935 AB - [EN]The ring-like cohesin complex plays an essential role in chromosome segregation, organization, and double-strand break repair through its ability to bring two DNA double helices together. Scc2 (NIPBL in humans) together with Scc4 functions as the... LA - eng PB - ScienceDirect KW - cohesin KW - cohesin loader KW - chromatin adapters KW - Saccharomyces cerevisiae KW - Mammals KW - Chromatids KW - RNA Polymerase II KW - Chromatin KW - Animals KW - Humans KW - Chromosome Segregation KW - Saccharomyces cerevisiae Proteins KW - Saccharomyces cerevisiae KW - Cell Cycle Proteins TI - Mediator recruits the cohesin loader Scc2 to RNA Pol II-transcribed genes and promotes sister chromatid cohesion. DO - 10.1016/j.cub.2022.05.019 T2 - Current biology VL - 32 M2 - 2884 ER -