TY - JOUR AU - Tornavaca, O. AU - Pascual, G. AU - Barreiro, M. L. AU - Grande, Maria Teresa AU - Carretero, A. AU - Riera, M. AU - Garcia-Arumi, E. AU - Bardaji, B. AU - González Núñez, María AU - Montero, M. A. AU - López-Novoa, José M. AU - Meseguer, A. PY - 2009 SN - 0009-7322 UR - http://hdl.handle.net/10366/155198 AB - [EN]Kidney androgen-regulated protein (KAP), a proximal tubule androgen-regulated gene, codes for a protein of unknown function. To investigate the consequences of KAP overexpression in kidney, we produced KAP transgenic mice and performed microarray... LA - eng PB - Lippincott Williams & Wilkins KW - Hypertension KW - Kidney KW - Androgens KW - Sex dimorphism KW - Transgenic mice KW - Reverse Transcriptase Polymerase Chain Reaction KW - Oxidative Stress KW - Hemodynamics KW - Glutathione Peroxidase KW - Gene Expression Regulation KW - Humans KW - DNA Damage KW - Kidney KW - Hypertension KW - Microscopy KW - Oligonucleotide Array Sequence Analysis KW - Blood Pressure KW - Catalase KW - Kidney Diseases KW - RNA KW - Proteins KW - Immunohistochemistry KW - Animals KW - Exons KW - Superoxide Dismutase KW - Polymerase Chain Reaction KW - Angiotensinogen KW - Mice TI - Kidney androgen-regulated protein transgenic mice show hypertension and renal alterations mediated by oxidative stress DO - 10.1161/CIRCULATIONAHA.108.808543 T2 - Circulation VL - 119 M2 - 1908 ER -