TY - JOUR AU - Mariñas del Collado, Irene AU - Rodríguez Díaz, Juan Manuel AU - Santos Martín, María Teresa PY - 2023 SN - 0169-7439 UR - http://hdl.handle.net/10366/156382 AB - [EN]The equation most commonly used to estimate a person’s blood alcohol concentration after consuming alcoholic drinks assumes zero-order kinetics in the ethanol elimination phase. This implies that the elimination process occurs in the body at a... LA - eng PB - ELSEVIER KW - Alcohol clearance KW - Ethanol pharmacokinetics KW - Widmark equation KW - Non-linear models KW - Optimal design of experiments KW - D-optimality KW - Covariance structure TI - Optimal designs for a non-linear model for the pharmacokinetics of ethanol elimination in the human body. DO - 10.1016/j.chemolab.2023.104839 T2 - Chemometrics and Intelligent Laboratory Systems VL - 238 M2 - 104839 ER -