TY  - JOUR 
AU  - Guerrero Arroyo, María Carmen
AU  - Martín Encabo, Susana
AU  - Fernández Medarde, Alberto
AU  - Santos de Dios, Eugenio Miguel
PY  - 2004
SN  - 0950-9232
UR  - http://hdl.handle.net/10366/156416
AB  - [ES]Anteriormente demostramos que la sobreexpresión exógena de C3G, un factor liberador de nucleótidos de guanina (GEF) para las proteínas Rap1 y R-Ras, bloquea la actividad formadora de focos de los oncogenes sis, Ras y v-raf en células NIH 3T3. En...
AB  - [EN]We showed previously that exogenous overexpression of C3G, a guanine nucleotide releasing factor (GEF) for Rap1 and R-Ras proteins, blocks the focus-forming activity of cotransfected, activated, sis, ras and v-raf oncogenes in NIH 3T3 cells. In...
LA  - eng
PB  - Springer Nature
KW  - C3G
KW  - Ras
KW  - Focus formation
KW  - Anchorageindependent growth
KW  - Transformation suppression
TI  - C3G-mediated suppression of oncogene-induced focus formation in fibroblasts involves inhibition of ERK activation, cyclin A expression and alterations of anchorage-independent growth
DO  - 10.1038/sj.onc.1207622
T2  - Oncogene
VL  - 23
M2  - 4885
ER  -