TY  - JOUR 
AU  - Fernández Medarde, Alberto
AU  - Esteban, Luis M.
AU  - Núñez, Alejandro
AU  - Porteros Herrero, Ángel Fernando
AU  - Tessarollo, Lino
AU  - Santos de Dios, Eugenio Miguel
PY  - 2002
SN  - 0270-7306
UR  - http://hdl.handle.net/10366/156691
AB  - [ES]Las proteínas Grf1 y Grf2 de mamíferos son factores de intercambio de nucleótidos de guanina (GEF) para las GTPasas Ras que comparten un alto grado de homología estructural, así como un nivel de expresión elevado en los tejidos del sistema...
AB  - [EN]The mammalian Grf1 and Grf2 proteins are Ras guanine nucleotide exchange factors (GEFs) sharing a high degree of structural homology, as well as an elevated expression level in central nervous system tissues. Such similarities raise questions...
LA  - eng
PB  - Taylor and Francis
KW  - RASGRF2
KW  - Knockout mice
KW  - Targeted disruption
KW  - Gene tergeting
KW  - Phenotypic analysis
KW  - Phenotype
KW  - Gene Targeting
TI  - Targeted disruption of Ras-Grf2 shows Its dispensability for mouse growth and development
DO  - 10.1128/MCB.22.8.2498-2504.2002
T2  - Molecular and Cellular Biology
VL  - 22
M2  - 2498
ER  -