TY - THES A3 - Santamaría Velilla, David A3 - Cappellen, David AU - Hita Román, Sergio de PY - 2023 UR - http://hdl.handle.net/10366/157901 AB - [EN] This thesis delves into the intricate regulation of the RAS-MAPK pathway in lung adenocarcinoma, where genetic alterations drive tumor progression by upregulating MAPK activity. Nonetheless, the tumor must keep a tight balance between positive... LA - eng KW - Tesis y disertaciones académicas KW - Universidad de Salamanca (España) KW - Tesis Doctoral KW - Academic dissertations KW - Cancer KW - LUAD KW - Mice KW - MAPK KW - CRISPR KW - KRAS KW - DUSP4 KW - Phosphatases KW - Bioinformatics KW - Poumon KW - Souris KW - Phosphatases KW - Cáncer KW - Ratones KW - Fosfatasas KW - Bioinformática KW - Medical Oncology TI - La régulation de la voie MAPK et ses conséquences dans l'adénocarcinome de poumon KRAS muté T2 - MAPK pathway modulation and its implications in KRAS mutant lung adenocarcinoma M3 - info:eu-repo/semantics/doctoralThesis DO - 10.14201/gredos.157901 ER -