TY  - JOUR 
AU  - Fuentes Martín, Raúl
AU  - Ayuda Durán, Pilar
AU  - Hanes, Robert
AU  - Gallego-Yerga, Laura
AU  - Wolterinck, Lisanne
AU  - Enserink, Jorrit M.
AU  - Álvarez Lozano, Raquel
AU  - Peláez Lamamie de C. Arroyo, Rafael
AU  - Fuentes Martín, Raúl
AU  - Ayuda-Durán, Pilar
AU  - Álvarez, Raquel
AU  - Peláez Lamamie de C. Arroyo, Rafael
PY  - 2024
SN  - 0223-5234
UR  - http://hdl.handle.net/10366/160431
AB  - [EN]Agents that cause apoptotic cell death by interfering with tubulin dynamics, such as vinblastine
and paclitaxel, are an important class of chemotherapeutics. Unfortunately, these compounds
are substrates for multidrug resistance (MDR) pumps,...
LA  - eng
PB  - Elsevier
KW  - Sulfonamides
KW  - Indole
KW  - Tubulin
KW  - SAR
KW  - Colchicine site
KW  - Antitumor
KW  - Mechanism
KW  - Resistance
KW  - Sulfonamides
KW  - Tubulin
KW  - Colchicine
TI  - Promising anti-proliferative indolic benzenesulfonamides alter mechanisms with sulfonamide nitrogen substituents
DO  - 10.1016/j.ejmech.2024.116617
T2  - European Journal of Medicinal Chemistry
VL  - 275
M2  - 116617
ER  -