TY - JOUR AU - Perez, MJ AU - Gonzalez-Sanchez, E AU - Gonzalez-Loyola, A AU - González de Buitrago Arriero, José Manuel AU - García Marín, José Juan PY - 2011 SN - 0007-1188 UR - http://hdl.handle.net/10366/162980 AB - [EN] BACKGROUND AND PURPOSE Mitochondria are involved in the toxicity of several compounds, retro-control of gene expression and apoptosis activation. The effect of mitochondrial genome (mtDNA) depletion on changes in ABC transporter protein... LA - eng PB - Wiley. British Pharmacological Society KW - ABC proteins; KW - paracetamol KW - bile acid KW - cholestasis KW - drug toxicity KW - liver KW - mitochondria KW - multidrug resistance KW - retrograde control KW - rho cells KW - DNA, Mitochondrial KW - Acetaminophen KW - Cholestasis TI - Mitochondrial genome depletion dysregulates bile acid‐ and paracetamol‐induced expression of the transporters Mdr1, Mrp1 and Mrp4 in liver cells DO - 10.1111/j.1476-5381.2010.01174.x T2 - British Journal of Pharmacology VL - 162 M2 - 1686 ER -