TY  - JOUR 
AU  - Robles-Valero, Javier
AU  - Lorenzo Martín, Luis Francisco
AU  - Menacho-Márquez, Mauricio
AU  - Fernández-Pisonero, Isabel
AU  - Abad, Antonio
AU  - Camós, Mireia
AU  - Toribio, María L
AU  - Espinosa, Lluis
AU  - Bigas, Anna
AU  - Bustelo, Xosé R.
PY  - 2017
UR  - http://hdl.handle.net/10366/166944
AB  - [EN]Rho guanine exchange factors (GEFs), the enzymes that stimulate Rho GTPases, are deemed as potential therapeutic targets owing to their protumorigenic functions. However, the understanding of the spectrum of their pathobiological roles in tumors...
LA  - eng
PB  - Elsevier Inc
KW  - Rho guanine exchange factors
KW  - Rho GTPases
KW  - T cell acute lymphoblastic leukemia
KW  - T-Lymphocytes
KW  - Signal Transduction
KW  - Proto-Oncogene Proteins c-vav
KW  - Tumor Suppressor Proteins
KW  - Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
KW  - Proto-Oncogene Proteins c-cbl
TI  - A Paradoxical Tumor-Suppressor Role for the Rac1 Exchange Factor Vav1 in T Cell Acute Lymphoblastic Leukemia.
DO  - 10.1016/j.ccell.2017.10.004
T2  - Cancer cell
VL  - 32
M2  - 608
ER  -