TY  - JOUR 
AU  - Suardiaz, Reynier
AU  - Siddiqui, Shakir Ali
AU  - Kwon, Hanna
AU  - van der Kamp, Marc W.
AU  - González Sánchez, Lola
AU  - Moody, Peter C. E.
AU  - Raven, Emma L.
AU  - Mulholland, Adrian J.
PY  - 2025
SN  - 1433-7851
UR  - http://hdl.handle.net/10366/167385
AB  - [EN]The active sites of heme enzymes have evolved to control the formation of highly reactive intermediates in oxidative catalysis. Proton delivery to the heme is essential, yet the mechanisms of proton delivery remain poorly understood. Here, we...
LA  - eng
PB  - WILEY
KW  - DFT cluster mode
KW  - Electric field
KW  - Heme peroxidase
KW  - Proton transfer
KW  - QM/MM
KW  - Solvent channel
TI  - Solvent Channels and Electric Fields Guide Proton Delivery to the Active Site of Heme Peroxidases
DO  - 10.1002/anie.202515743
T2  - Angewandte Chemie International Edition
ER  -