TY - JOUR AU - García Macia, Marina AU - Santos Ledo, Adrián AU - Leslie, Jack AU - Paish, Hannah L AU - Collins, Amy L AU - Scott, Rebecca S AU - Watson, Abigail AU - Burgoyne, Rachel A AU - White, Steve AU - French, Jeremy AU - Hammond, John AU - Borthwick, Lee A AU - Mann, Jelena AU - Bolaños Hernández, Juan Pedro AU - Korolchuk, Viktor I AU - Oakley, Fiona AU - Mann, Derek A PY - 2021 SN - 0270-9139 UR - http://hdl.handle.net/10366/167680 AB - [EN]NAFLD is the most common hepatic pathology in western countries and no treatment is currently available. NAFLD is characterized by the aberrant hepatocellular accumulation of fatty acids in the form of lipid droplets (LDs). Recently, it was shown... LA - eng KW - Liver KW - Autophagy KW - Plin KW - mTor KW - Hepatosteatosis KW - Lipophagy KW - Mouse KW - Microscopy KW - Animals KW - Signal Transduction KW - Humans KW - Hepatocytes KW - Autophagy KW - Fatty Liver KW - Mice TI - A mammalian target of rapamycin-perilipin 3 (mTORC1-Plin3) pathway is essential to activate lipophagy and protects against hepatosteatosis DO - 10.1002/hep.32048 T2 - Hepatology VL - 74 M2 - 3441 ER -